BackgroundThis gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.
DescriptionHEY1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ9Y5J3
PurificationAffinity Purified
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 50-150 of human HEY1 (NP_001269780.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesHEY1; BHLHb31; CHF2; HERP2; HESR1; HRT-1; OAF1; hHRT1; hairy/enhancer-of-split related with YRPW motif protein 1
ApplicationWB, IF