BackgroundGlutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
DescriptionGSS Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.01% thiomersal, 50% glycerol,pH7.3
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP48637
PurificationAffinity Purification
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 373-474 of human GSS (NP_000169.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesGSS; GSHS; HEL-S-64p; HEL-S-88n; glutathione synthetase
ApplicationWB, IF/ICC; Recommended Dilutions: WB 1:500 - 1:2000, IF/ICC 1:50 - 1:200