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Fcmr Polyclonal Antibody

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Western blot
All lanes:Fcmr Polyclonal Antibody at 2ug/ml
Lane 1: rat spleen tissue
Lane 2: rat kidney tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 47kDa
Observed band size: 47kDa
Application: ELISA, WB
Areas of Research: Apoptosis & Cell Death
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Mouse, Rat
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A56202-02020 µg $99.00 
A56202-05050 µg $256.00 
A56202-100100 µg $359.00 
Order now & get it by Wednesday, September 4th  
Product Overview

Background
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Description
Fcmr Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Mouse, Rat

Isotype
IgG

Uniprot ID
A1KXC4

Purification
>95%, Protein G purified

Immunogen
Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Regulator of Fas-induced apoptosis Toso, Faim3, Toso

Application
ELISA, WB; Recommended dilution: WB:1:1000-1:5000

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