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Introduction to Epigenetics

DNA Damage & Repair Antibodies

Cells undergo DNA damage constantly from exogenous and endogenous sources. Some of these sources include UV-light, ionizing radiation, alkylating agents and other environmental DNA damaging agents, as well as other sources derived spontaneously from cellular metabolism, such as reactive oxygen species. DNA damaging agents can cause a number of DNA lesions, including adducts, apurinic/apyrimidinic sites (AP sites), single-strand and double-strand DNA breaks. Left unrepaired, these DNA lesions could result in mutations, senescence, or induction of cell death which could lead to the development of neurodegeneration, cancer and other diseases.

In order to maintain genomic integrity, cells have developed the DNA damage response (DDR) pathway which allows cells to recognize the DNA damage and facilitate recruitment and activation of DNA repair proteins. Members of the phosphatidyl-inositol 3-kinase like protein kinase (PIKK) family, such as ATM, ATR and DNA-PK, are involved in this response, as well as a few members of the poly (ADP-ribose) polymerase (PARP) family.

Several DNA repair pathways exist to correct the DNA lesions depending on the particular form of DNA damage. For instance, the base excision repair (BER) and the mismatch repair (MMR) pathways mend damaged or mispaired DNA bases by excising the damaged base or by replacing mispaired bases with correct ones. Nucleotide excision repair (NER) fixes DNA lesions such as intrastrand crosslinks by removing a larger oligonucleotide DNA fragment; while double-strand breaks are generally repaired by non-homology end-joining (NHEJ) or by homology-directed repair (HDR).

What makes buying antibodies from EpiGentek different?

At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:

  • No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
  • 100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
  • Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
  • Trial Sizes Available: 10 & 20 µg options available on over 5,000 antibodies in our catalog.

Result Pages: [<< Prev]  ... 6  7  8  9  [Next >>]  Displaying 101 to 120 (of 169 products)
POLK Polyclonal Antibody, Biotin Conjugated
POLK Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A69298-05050 µg $249.00 Add to Cart
A69298-100100 µg $399.00 Add to Cart
Antibodies
POLK Polyclonal Antibody, FITC Conjugated
POLK Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A69297-05050 µg $249.00 Add to Cart
A69297-100100 µg $399.00 Add to Cart
Antibodies
POLK Polyclonal Antibody, HRP Conjugated
POLK Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A69296-05050 µg $249.00 Add to Cart
A69296-100100 µg $399.00 Add to Cart
Antibodies
RAD17 Polyclonal Antibody
RAD17 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A50440-02020 µg $99.00 Add to Cart
A50440-05050 µg $256.00 Add to Cart
A50440-100100 µg $359.00 Add to Cart
Antibodies
RAD17 Polyclonal Antibody, Biotin Conjugated
RAD17 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A50443-05050 µg $256.00 Add to Cart
A50443-100100 µg $359.00 Add to Cart
Antibodies
RAD17 Polyclonal Antibody, FITC Conjugated
RAD17 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A50442-05050 µg $256.00 Add to Cart
A50442-100100 µg $359.00 Add to Cart
Antibodies
RAD17 Polyclonal Antibody, HRP Conjugated
RAD17 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A50441-05050 µg $256.00 Add to Cart
A50441-100100 µg $359.00 Add to Cart
Antibodies
RAD18 Polyclonal Antibody
RAD18 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A56282-02020 µg $99.00 Add to Cart
A56282-05050 µg $256.00 Add to Cart
A56282-100100 µg $359.00 Add to Cart
Antibodies
RAD18 Polyclonal Antibody, Biotin Conjugated
RAD18 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A56285-05050 µg $256.00 Add to Cart
A56285-100100 µg $359.00 Add to Cart
Antibodies
RAD18 Polyclonal Antibody, FITC Conjugated
RAD18 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A56284-05050 µg $256.00 Add to Cart
A56284-100100 µg $359.00 Add to Cart
Antibodies
RAD18 Polyclonal Antibody, HRP Conjugated
RAD18 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A56283-05050 µg $256.00 Add to Cart
A56283-100100 µg $359.00 Add to Cart
Antibodies
RAD23A Polyclonal Antibody
RAD23A Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A53961-02020 µg $99.00 Add to Cart
A53961-05050 µg $256.00 Add to Cart
A53961-100100 µg $359.00 Add to Cart
Antibodies
RAD23A Polyclonal Antibody, Biotin Conjugated
RAD23A Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A53964-05050 µg $256.00 Add to Cart
A53964-100100 µg $359.00 Add to Cart
Antibodies
RAD23A Polyclonal Antibody, FITC Conjugated
RAD23A Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A53963-05050 µg $256.00 Add to Cart
A53963-100100 µg $359.00 Add to Cart
Antibodies
RAD23A Polyclonal Antibody, HRP Conjugated
RAD23A Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A53962-05050 µg $256.00 Add to Cart
A53962-100100 µg $359.00 Add to Cart
Antibodies
RAD23B Polyclonal Antibody
RAD23B Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A50444-02020 µg $99.00 Add to Cart
A50444-05050 µg $256.00 Add to Cart
A50444-100100 µg $359.00 Add to Cart
Antibodies
RAD23B Polyclonal Antibody, Biotin Conjugated
RAD23B Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A50447-05050 µg $256.00 Add to Cart
A50447-100100 µg $359.00 Add to Cart
Antibodies
RAD23B Polyclonal Antibody, FITC Conjugated
RAD23B Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A50446-05050 µg $256.00 Add to Cart
A50446-100100 µg $359.00 Add to Cart
Antibodies
RAD23B Polyclonal Antibody, HRP Conjugated
RAD23B Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A50445-05050 µg $256.00 Add to Cart
A50445-100100 µg $359.00 Add to Cart
Antibodies
RAD54L2 Polyclonal Antibody
RAD54L2 Polyclonal Antibody

Application: WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
A-6700-05050 µl $189.00 Add to Cart
A-6700-100100 µl $299.00 Add to Cart
Antibodies
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