BackgroundDouble-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
DescriptionNHEJ1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ9H9Q4
PurificationAffinity Purified
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human NHEJ1 (NP_079058.1)
StorageShipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.
Alternative NamesNHEJ1; XLF
ApplicationWB, IHC, IF; Recommended dilution: WB 1:200 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200
