BackgroundInvolved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate.
DescriptionmutT Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityEscherichia coli
IsotypeIgG
Uniprot IDP08337
Purification>95%, Protein G purified
ImmunogenRecombinant Escherichia coli 8-oxo-dGTP diphosphatase protein (1-129AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative Names8-oxo-dGTP diphosphatase, 8-oxo-dGTPase, 7, 8-dihydro-8-oxoguanine-triphosphatase, Mutator protein MutT, dGTP pyrophosphohydrolase, mutT, b0099, JW0097
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000
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