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DNMT ELISA Easy Kit

DNA Damage & Repair Antibodies

Cells undergo DNA damage constantly from exogenous and endogenous sources. Some of these sources include UV-light, ionizing radiation, alkylating agents and other environmental DNA damaging agents, as well as other sources derived spontaneously from cellular metabolism, such as reactive oxygen species. DNA damaging agents can cause a number of DNA lesions, including adducts, apurinic/apyrimidinic sites (AP sites), single-strand and double-strand DNA breaks. Left unrepaired, these DNA lesions could result in mutations, senescence, or induction of cell death which could lead to the development of neurodegeneration, cancer and other diseases.

In order to maintain genomic integrity, cells have developed the DNA damage response (DDR) pathway which allows cells to recognize the DNA damage and facilitate recruitment and activation of DNA repair proteins. Members of the phosphatidyl-inositol 3-kinase like protein kinase (PIKK) family, such as ATM, ATR and DNA-PK, are involved in this response, as well as a few members of the poly (ADP-ribose) polymerase (PARP) family.

Several DNA repair pathways exist to correct the DNA lesions depending on the particular form of DNA damage. For instance, the base excision repair (BER) and the mismatch repair (MMR) pathways mend damaged or mispaired DNA bases by excising the damaged base or by replacing mispaired bases with correct ones. Nucleotide excision repair (NER) fixes DNA lesions such as intrastrand crosslinks by removing a larger oligonucleotide DNA fragment; while double-strand breaks are generally repaired by non-homology end-joining (NHEJ) or by homology-directed repair (HDR).
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XRCC5 Polyclonal Antibody, HRP Conjugated
XRCC5 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A61809-05050 µg $256.00 Add to Cart
A61809-100100 µg $359.00 Add to Cart
Antibodies
XRCC6 Polyclonal Antibody
XRCC6 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A56647-02020 µg $99.00 Add to Cart
A56647-05050 µg $256.00 Add to Cart
A56647-100100 µg $359.00 Add to Cart
Antibodies
XRCC6 Polyclonal Antibody, Biotin Conjugated
XRCC6 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A56650-05050 µg $256.00 Add to Cart
A56650-100100 µg $359.00 Add to Cart
Antibodies
XRCC6 Polyclonal Antibody, FITC Conjugated
XRCC6 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A56649-05050 µg $256.00 Add to Cart
A56649-100100 µg $359.00 Add to Cart
Antibodies
XRCC6 Polyclonal Antibody, HRP Conjugated
XRCC6 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A56648-05050 µg $256.00 Add to Cart
A56648-100100 µg $359.00 Add to Cart
Antibodies
XRRA1 Polyclonal Antibody
XRRA1 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A65478-02020 µg $99.00 Add to Cart
A65478-05050 µg $256.00 Add to Cart
A65478-100100 µg $359.00 Add to Cart
Antibodies
XRRA1 Polyclonal Antibody, Biotin Conjugated
XRRA1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65481-05050 µg $256.00 Add to Cart
A65481-100100 µg $359.00 Add to Cart
Antibodies
XRRA1 Polyclonal Antibody, FITC Conjugated
XRRA1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65480-05050 µg $256.00 Add to Cart
A65480-100100 µg $359.00 Add to Cart
Antibodies
XRRA1 Polyclonal Antibody, HRP Conjugated
XRRA1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65479-05050 µg $256.00 Add to Cart
A65479-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]  ... 6  7  8  9  Displaying 161 to 169 (of 169 products)
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