BackgroundEssential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
DescriptionRAD17 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDO75943
Purification>95%, Protein G purified
ImmunogenRecombinant Human Cell cycle checkpoint protein RAD17 protein (1-270AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCell cycle checkpoint protein RAD17, hRad17, RF-C/activator 1 homolog, RAD17, R24L
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000
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