BackgroundThis gene encodes a leucine zipper transcription factor, belonging to the DNA binding proteins. Operating as a homodimer, it binds to the cAMP-responsive element, an octameric palindrome. It gets phosphorylated by various kinases, triggering gene transcription upon hormonal cAMP pathway stimulation. Alternative splicing yields distinct isoforms from several transcript variants.
DescriptionCREB1 Recombinant Monoclonal Antibody [21E3]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman, Mouse, Rat
IsotypeRabbit IgG
Uniprot IDP16220
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human CREB1
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesCyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1), CREB1
ApplicationELISA, WB, FC; Recommended dilution: WB:1:500-1:2000, FC:1:50-1:200