BackgroundHas (dihydro)ceramide synthesis activity with relatively broad substrate specificity, but a preference for C18:0 and other middle- to long-chain fatty acyl-CoAs. It is crucial for the synthesis of very long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation.
DescriptionCERS3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDQ8IU89
PurificationProtein G purified
ImmunogenRecombinant Human Ceramide synthase 3 protein (59-134AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCeramide synthase 3, CerS3, Dihydroceramide synthase 3, LAG1 longevity assurance homolog 3, CERS3, LASS3
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:5000