BackgroundCela2a encodes a serine protease enzyme that hydrolyzes elastin. This gene is greatly expressed in acinar cells of the pancreas where the encoded preproprotein goes through processing which includes signal peptide cleavage to generate an inactive zymogen. Active elastase enzyme is generated by the removal of N-terminal activation peptide from the zymogen by trypsin. In addition, this gene is expressed in the mouse epidermis where it is involved in pro-filaggrin processing.
DescriptionCela2a Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityMouse
IsotypeIgG
Uniprot IDP05208
Purification>95%, Protein G purified
ImmunogenRecombinant Mouse Chymotrypsin-like elastase family member 2A protein (31-271AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesElastase-2 Elastase-2A Cela2a Ela-2, Ela2, Ela2a
ApplicationELISA, WB; Recommended dilution: WB:1:1000-1:5000