BackgroundPlays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
DescriptionCDX1 Recombinant Monoclonal Antibody [11E10]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP47902
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human CDX1
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesHomeobox protein CDX-1 (Caudal-type homeobox protein 1), CDX1
ApplicationELISA, WB, IF; Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200