BackgroundInvolved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
DescriptionCASP2 Recombinant Monoclonal Antibody [7E5]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP42575
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Caspase-2
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesCaspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18, Caspase-2 subunit p13, Caspase-2 subunit p12], CASP2, ICH1 NEDD2
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:5000