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C3 Polyclonal Antibody

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Western blot All lanes: Complement C3 antibody at 20ug/ml+ Human high value serumGoat polyclonal to rabbit at 1/10000 dilution Predicted band size: 187,61 kDa Observed band size: 186 kDa
Application: ELISA, WB
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A55275-02020 µg $59.00 
A55275-05050 µg $256.00 
A55275-100100 µg $359.00 
Availability: Usually Ships Within 1 Week 
Product Overview

Background
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. The short isoform hasB-cell stimulatory activity. Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2.

Description
C3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human, Mouse

Isotype
IgG

Uniprot ID
P01027

Purification
>95%, Protein G purified

Immunogen
Recombinant Mouse Complement C3 protein (1321-1663AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
HSE-MSF, ASP, C3adesArg, C3

Application
ELISA, WB; Recommended dilution: WB:1:1000-1:5000

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