BackgroundDNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
DescriptionBRIP1 Recombinant Monoclonal Antibody [27F4]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ9BX63
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human BRIP1
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesFanconi anemia group J protein (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1), BRIP1, BACH1 FANCJ
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:2000
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