BackgroundInhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).
DescriptionAXIN2 Recombinant Monoclonal Antibody [3G6]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ9Y2T1
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human AXIN2
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesAxin-2, Axin-like protein, Axil, Axis inhibition protein 2, Conductin, AXIN2
ApplicationELISA