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SET1 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human testis tissue using SET1 Polyclonal Antibody at dilution of 1:100
Application: ELISA, IHC
Areas of Research: Histone Methylation & Demethylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-3011-02020 µg $99.00 
A-3011-05050 µg $242.00 
A-3011-100100 µg $399.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
The Set1/COMPASS histone methyltransferase complex contains the SET1 histone methyltransferase protein. It functions as a transcriptional co-activator and methylates histone H3 at Lys4 (H3K4). Although first identified in yeast, SET1-related proteins are also found within mammals, including proteins SET1A, SET1B, MLL1, MLL2, MLL3, and MLL4. These proteins work together in a complex to methylate histone H3 at Lys4. In addition, SET1/COMPASS histone methyltransferase complexes are thought to play a role in leukemogenesis due to a significant amount of hematological malignancies containing MLL translocations.

Description
SET1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit

Formulation
Liquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4

Specificity
Human

Isotype
IgG

Uniprot ID
O15047

Purification
Protein G purified

Immunogen
Recombinant human Histone-lysine N-methyltransferase SETD1A protein (188-304AA)

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.43) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1), SETD1A, KIAA0339 KMT2F SET1 SET1A

Application
ELISA, IHC; Recommended dilution: IHC:1:20-1:200

 

VCU0006

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