The Set1/COMPASS histone methyltransferase complex contains the SET1 histone methyltransferase protein. It functions as a transcriptional co-activator and methylates histone H3 at Lys4 (H3K4). Although first identified in yeast, SET1-related proteins are also found within mammals, including proteins SET1A, SET1B, MLL1, MLL2, MLL3, and MLL4. These proteins work together in a complex to methylate histone H3 at Lys4. In addition, SET1/COMPASS histone methyltransferase complexes are thought to play a role in leukemogenesis due to a significant amount of hematological malignancies containing MLL translocations.
SET1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
Protein G purified
Recombinant Human Histone-lysine N-methyltransferase SETD1A protein (188-304AA)
Shipped at 4°C. Aliquot store at -20°C . Avoid repeated freeze / thaw cycles.
Histone-lysine N-methyltransferase SETD1A antibody, hSET1A antibody, KMT2F antibody, Lysine N methyltransferase 2F antibody, SET domain containing protein 1A antibody, Set1 Ash2 histone methyltransferase complex subunit SET1 antibody, SET1A antibody, SETD1A antibody