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ATIC Polyclonal Antibody

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Western blot analysis of extracts of various cell lines, using ATIC Polyclonal Antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Exposure time: 90s.
Application: WB
Areas of Research: Nucleotide Metabolism Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
Trial Size Available: A72346-020
100% Guarantee: 6 months
Catalog No.SizePriceQty
A72346-05050 µl $256.00 
A72346-100100 µl $359.00 
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Product Overview

Background
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

Description
ATIC Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human

Isotype
IgG

Uniprot ID
P31939

Purification
Affinity Purification

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ATIC (NP_004035.2).

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Alternative Names
ATIC; AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH; bifunctional purine biosynthesis protein PURH

Application
WB; Recommended dilution: WB 1:500 - 1:2000

User Guide & MSDS

[User Guide]*
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