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ALKBH3 Polyclonal Antibody

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Immunohistochemistry analysis of human testis tissue using ALKBH3 Polyclonal Antibody at dilution of 1:100
Immunocytochemistry analysis of human skeletal muscle tissue using ALKBH3 Polyclonal Antibody at dilution of 1:100
Immunofluorescent analysis of PC3 cells using ALKBH3 Polyclonal Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L)
Application: ELISA, IF, IHC
Areas of Research: DNA Methylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A57365-02020 µg $99.00 
A57365-05050 µg $256.00 
A57365-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.

Description
ALKBH3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q96Q83

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 protein (1-170AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Alkylated DNA repair protein alkB homolog 3, DEPC-1, Prostate cancer antigen 1, ABH3, DEPC1, ALKBH3

Application
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

User Guide & MSDS

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