BackgroundThis gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.
DescriptionADAMTS13 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ76LX8
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1300-1400 of human ADAMTS13 (NP_620594.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesADAMTS13; ADAM-TS13; ADAMTS-13; C9orf8; VWFCP; vWF-CP; ADAM metallopeptidase with thrombospondin type 1 motif 13
ApplicationWB, IF; Recommended dilution: WB 1:500 - 1:2000, IF 1:50 - 1:200
