BackgroundFunctions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis.
DescriptionACTR3 Recombinant Monoclonal Antibody [7E5]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman, Mouse, Rat
IsotypeRabbit IgG
Uniprot IDP61158
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Arp3
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesActin-related protein 3 (Actin-like protein 3), ACTR3, ARP3
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:5000