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ABL1 Polyclonal Antibody

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Application: IF, IHC, WB
Areas of Research: Intracellular Kinase & Adaptor Protein Antibodies
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: A70768-020
100% Guarantee: 6 months
Catalog No.SizePriceQty
A70768-05050 µl $256.00 
A70768-100100 µl $359.00 
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Product Overview

Background
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.

Description
ABL1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
P00519

Purification
Affinity Purification

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 490-590 of human ABL1 (NP_005148.2).

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Alternative Names
ABL1; ABL; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl; tyrosine-protein kinase ABL1

Application
WB, IHC, IF; Recommended dilution: WB 1:500 - 1:2000, IHC 1:100 - 1:200, IF 1:50 - 1:200

User Guide & MSDS

[User Guide]*
*Always use the actual User Guide that shipped with your product. Is the above file locked? You can also request user guides by emailing info@epigentek.com along with your contact information and institution name.

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