BackgroundLigand for members of the frizzled family of seven transmembrane receptors. Plays a role in ventral mesodermal patterning during embryogenesis. Mimics Nieuwkoop center activity. Causes dorsal mesodermal differentiation of animal cap ectoderm when coexpressed with noggin and nuclear, sequence-specific DNA-binding protein xBra. None of these molecules causes dorsal mesoderm formation when expressed alone.
Descriptionwnt8 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityXenopus laevis
IsotypeIgG
Uniprot IDP28026
Purification>95%, Protein G purified
ImmunogenRecombinant Xenopus laevis Protein Wnt-8 protein (23-358AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesXWnt-8, wnt8
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500