Histone H3K9me2 Dimethyl Peptide

Description
Synthesized dimethyl histone H3-K9 peptide derived from residues within 1-100 of human histone H3.

Purity
>90% by HPLC analysis

Concentration
0.27 mg/ml (100 µM)

Formulation
Tris-buffer solution

Storage
-20°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.

Application
Enzyme activity
Histone affinity precipitation assay

Handling Recommendations
For maximum recovery of the products, centrifuge the vial prior to opening the cap.

Usage
Research use only.

1. Kim YY et. al. (February 2024). KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nat Commun. 15(1):1703.
2. Suzuki T et. al. (May 2023). Crucial role of iron in epigenetic rewriting during adipocyte differentiation mediated by JMJD1A and TET2 activity. Nucleic Acids Res.