Histone H3K27me3 Trimethyl Peptide

Description
Synthesized trimethyl histone H3-K27 peptide derived from residues within 1-100 of human histone H3.

Purity
>90% by HPLC analysis

Concentration
0.3 mg/ml (100 µM)

Formulation
Tris-buffer solution

Storage
-20°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.

Application
Enzyme activity
Histone affinity precipitation assay

Handling Recommendations
For maximum recovery of the products, centrifuge the vial prior to opening the cap.

Usage
Research use only.

1. Ahanger SH et. al. (July 2026). Subnuclear genome compartmentalization controls bivalent chromatin activity. Nature. PubMed: 42486990
2. Ahanger SH et. al. (August 2024). Spatial 3D genome organization controls the activity of bivalent chromatin during human neurogenesis. bioRxiv.
3. Xin X et. al. (June 2024). Temperature-dependent jumonji demethylase modulates flowering time by targeting H3K36me2/3 in Brassica rapa. Nat Commun. 15(1):5470.