TLR7 Recombinant Monoclonal Antibody [6E5]

Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Description
TLR7 Recombinant Monoclonal Antibody [6E5]. Unconjugated. Raised in: HEK293F Cell.

Formulation
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Specificity
Human

Isotype
Rabbit IgG

Uniprot ID
Q9NYK1

Purification
Affinity Chromatography

Immunogen
A synthesized peptide derived from human TLR7

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
Toll-like receptor 7, TLR7

Application
ELISA, IHC; Recommended dilution: IHC:1:50-1:200