BackgroundProbable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
DescriptionTIMM8B Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9Y5J9
Purification>95%, Protein G purified
ImmunogenRecombinant Human Mitochondrial import inner membrane translocase subunit Tim8 B protein (33-83AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesMitochondrial import inner membrane translocase subunit Tim8 B, TIMM8B, DDP2, DDPL, TIM8B, DDP-like protein, Deafness dystonia protein 2
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200