BackgroundComponent of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). Expression seems to slow down and down-regulate MHC class I surface expression.
DescriptionTAPBPL Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9BX59
Purification>95%, Protein G purified
ImmunogenRecombinant Human Tapasin-related protein (201-468AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesTapasin-related protein, TAPASIN-R, TAP-binding protein-like, TAP-binding protein-related protein, TAPBP-R, Tapasin-like, TAPBPL
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200