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MGMT Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human kidney at dilution of 1:20
Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:20
Application: ELISA, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A52416-02020 µg $99.00 
A52416-05050 µg $256.00 
A52416-100100 µg $359.00 
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Product Overview

Background
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Description
MGMT Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
P16455

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Methylated-DNA--protein-cysteine methyltransferase protein (4-207AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
MGMT

Application
ELISA, IHC; Recommended dilution: IHC:1:20-1:200

User Guide & MSDS

[User Guide]*
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