Product Overview
Background
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Description
MGMT Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
Specificity
Human
Isotype
IgG
Uniprot ID
P16455
Purification
>95%, Protein G purified
Immunogen
Recombinant Human Methylated-DNA--protein-cysteine methyltransferase protein (4-207AA)
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative Names
MGMT
Application
ELISA