Product Overview
Background
May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. Has very low ribonuclease activity.
Description
ANG1 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
Specificity
Bovine
Isotype
IgG
Uniprot ID
P10152
Purification
>95%, Protein G purified
Immunogen
Recombinant Bovine Angiogenin-1 protein (24-148AA)
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative Names
ANG1, ANG
Application
ELISA