BackgroundSmall GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 (PubMed:25443296). Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6 (PubMed:25443296). Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25.
DescriptionIFT27 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9BW83
Purification>95%, Protein G purified
ImmunogenRecombinant Human Intraflagellar transport protein 27 homolog protein (1-186AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesPutative GTP-binding protein RAY-like, Rab-like protein 4, IFT27, RABL4, RAYL
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200