BackgroundHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
DescriptionHistone H4R3 Monomethyl (H4R3me1) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationPBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% glycerol.
SpecificityHuman
IsotypeIgG
Uniprot IDP62805
PurificationAffinity Purified
ImmunogenSynthetic Peptide
StorageShipped at 4°C. Aliquot store at -20°C . Avoid repeated freeze / thaw cycles.
Alternative NamesH4R3me1, H4, H4/n, H4F2, H4FN, FO108, HIST2H4, H4 Arginine 3 me1
ApplicationWB; Recommended dilution: WB:1:1000-2000