BackgroundEssential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans.
DescriptionGAA Recombinant Monoclonal Antibody [5E5]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP10253
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human GAA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesLysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase, 70 kDa lysosomal alpha-glucosidase], GAA
ApplicationELISA, IHC; Recommended dilution: IHC:1:50-1:200