BackgroundEGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro.
DescriptionEGF Recombinant Monoclonal Antibody [18B12]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP01133
PurificationAffinity-chromatography
ImmunogenA synthesized peptide derived from Human EGF
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesPro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)], EGF
ApplicationELISA, IHC, FC; Recommended dilution: IHC:1:50-1:200, FC:1:50-1:200