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DKK1 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human placenta tissue at dilution of 1:100
Immunohistochemistry of paraffin-embedded human glioma cancer at dilution of 1:100
Immunofluorescent analysis of U251 cells at a dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Application: ELISA, IF, IHC
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A64088-02020 µg $99.00 
A64088-05050 µg $256.00 
A64088-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Description
DKK1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
O94907

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Dickkopf-related protein 1 protein (33-266AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK, DKK1, UNQ492/PRO1008

Application
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

User Guide & MSDS

[User Guide]*
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