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CLEC4E Polyclonal Antibody

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Western blot
All lanes: CLEC4E Polyclonal Antibody at 0.3ug/ml+ Mouse spleen tissue
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 25 kDa
Observed band size: 25 kDa
Application: ELISA, IF, IHC
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A58586-02020 µg $99.00 
A58586-05050 µg $256.00 
A58586-100100 µg $359.00 
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Product Overview

Background
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

Description
CLEC4E Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q9ULY5

Purification
>95%, Protein G purified

Immunogen
Recombinant Human C-type lectin domain family 4 member E protein (41-219AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
C-type lectin domain family 4 member E, CLEC4E, CLECSF9, MINCLE, UNQ218/PRO244, C-type lectin superfamily member 9, Macrophage-inducible C-type lectin

Application
ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500

User Guide & MSDS

[User Guide]*
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