BackgroundInteracts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
DescriptionCENPB Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP07199
Purification>95%, Protein G purified
ImmunogenRecombinant Human Major centromere autoantigen B protein (1-165AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesMajor centromere autoantigen B, Centromere protein B, CENP-B, CENPB
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200