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CD45 Monoclonal Antibody [RMC049A]

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Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A68406-05050 µl $249.00 
A68406-100100 µl $399.00 
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Product Overview

Background
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).

Description
CD45 Monoclonal Antibody , clone RMC049A. Unconjugated. Raised in: Rabbit.

Concentration
Inquire

Formulation
Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Specificity
Human

Isotype
IgG

Uniprot ID
P08575

Purification
Affinity Purified

Immunogen
A synthesized peptide

Storage
Shipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, L-CA, T200, CD45, PTPRC

Application
ELISA

VCU0006

User Guide & MSDS

[User Guide]*
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Product Citations

Lianghong Peng et. al. (May 2018). A study on how bone marrow-derived MSCs inhibit rejection reaction of alkali burn-induced corneal neovascularization Int J Clin Exp Med. 11(5):4859-4866.

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