Epigentek Home
 
EpiGentek Guarantee

C3 Polyclonal Antibody

Share:

Write a Review
Immunohistochemistry of paraffin-embedded human prostate using C3 Polyclonal Antibody at dilution of 1:20
Immunohistochemistry analysis of human cervical cancer using C3 Polyclonal Antibody at dilution of 1:100
Immunocytochemistry analysis of human colon cancer using C3 Polyclonal Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using C3 Polyclonal Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L)
Application: ELISA, IF, IHC
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A52432-02020 µg $59.00 
A52432-05050 µg $256.00 
A52432-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Ref. 5 Ref. 11 Ref. 14 Ref. 15 Ref. 16 Ref. 22 Ref. 25 Ref. 30 Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. Ref. 5 Ref. 11 Ref. 14 Ref. 15 Ref. 16 Ref. 22 Ref. 25 Ref. 30 Acylation stimulating protein (ASP): adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for GPR77. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of GPR77.

Description
C3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
P01024

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Complement C3 protein (26-225AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3, CPAMD1

Application
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

User Guide & MSDS

[User Guide]*
*Always use the actual User Guide that shipped with your product. Is the above file locked? You can also request user guides by emailing info@epigentek.com along with your contact information and institution name.

Epigentek Rewards
Related Products
Epigentek is an epigenetics company that specializes in epigenetic kits, antibodies, reagents, and services for epigenetic research in DNA methylation, histone modification, and chromatin studies. Terms & Conditions | Privacy Policy | Site Map
Copyright © 2017 Epigentek Group Inc. All rights reserved.