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B4GAT1 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human kidney at dilution 1:100
Immunohistochemistry of paraffin-embedded human brain at dilution 1:100
Application: ELISA, IHC
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A50077-02020 µg $99.00 
A50077-05050 µg $256.00 
A50077-100100 µg $359.00 
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Product Overview

Background
Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE, during synthesis of phosphorylated O-mannosyl glycan (PubMed:25279699, PubMed:25279697). Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:25279697). Required for axon guidance; via its function in O-mannosylation of alpha-dystroglycan (DAG1).

Description
B4GAT1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
O43505

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Beta-1,4-glucuronyltransferase 1 protein (161-415AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Beta-1, 4-glucuronyltransferase 1, I-beta-1, 3-N-acetylglucosaminyltransferase, N-acetyllactosaminide beta-1, 3-N-acetylglucosaminyltransferase, Poly-N-acetyllactosamine extension enzyme, UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 1, B4GAT1, B3GNT1

Application
ELISA, IHC; Recommended dilution: IHC:1:20-1:200

User Guide & MSDS

[User Guide]*
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