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APAF1 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human skin tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human lung cancer tissue at dilution 1:100
Application: ELISA, IF, IHC
Areas of Research: Apoptosis & Cell Death
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A58094-02020 µg $59.00 
A58094-05050 µg $256.00 
A58094-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Description
APAF1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
O14727

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Apoptotic protease-activating factor 1 protein (104-415AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Apoptotic protease-activating factor 1, APAF-1, APAF1, KIAA0413

Application
ELISA, IHC, IF; Recommended dilution: IHC:1:50-1:200, IF:1:50-1:500

User Guide & MSDS

[User Guide]*
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