APAF1 Polyclonal Antibody, Biotin Conjugated

Background
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Description
APAF1 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
O14727

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Apoptotic protease-activating factor 1 protein (104-415AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Apoptotic protease-activating factor 1, APAF-1, APAF1, KIAA0413

Application
ELISA; Recommended dilution: ELISA 1:500-1:1000