BackgroundComponent of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
DescriptionAKTIP Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9H8T0
PurificationProtein G purified
ImmunogenRecombinant Human AKT-interacting protein (1-292AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesFt1, Fused toes protein homolog, FTS, AKTIP
ApplicationELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200
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