BackgroundDownstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
DescriptionWASF2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4
SpecificityHuman
IsotypeIgG
Uniprot IDQ9Y6W5
PurificationProtein G purified
ImmunogenRecombinant Human Wiskott-Aldrich syndrome protein family member 2 protein (243-317AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesWiskott-Aldrich syndrome protein family member 2, WASP family protein member 2, Protein WAVE-2, Verprolin homology domain-containing protein 2, WASF2
ApplicationELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200