BackgroundActs as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
DescriptionVPS50 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ96JG6
Purification>95%, Protein G purified
ImmunogenRecombinant Human Syndetin protein (1-250AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesSyndetin1, Coiled-coil domain-containing protein 132Curated, EARP/GARPII complex subunit VPS50, VPS50
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200