BackgroundProbable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process.
DescriptionTDRD9 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ8NDG6
Purification>95%, Protein G purified
ImmunogenRecombinant Human Putative ATP-dependent RNA helicase TDRD9 protein (286-585AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesPutative ATP-dependent RNA helicase TDRD9, Tudor domain-containing protein 9, TDRD9, C14orf75
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200