BackgroundPlays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.
DescriptionTCEAL7 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9BRU2
Purification>95%, Protein G purified
ImmunogenRecombinant Human Transcription elongation factor A protein-like 7 protein (1-100AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesTranscription elongation factor A protein-like 7, TCEA-like protein 7, TCEAL7, Transcription elongation factor S-II protein-like 7
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000