BackgroundGeneral coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
DescriptionSUB1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP53999
Purification>95%, Protein G purified
ImmunogenRecombinant Human Activated RNA polymerase II transcriptional coactivator p15 protein (2-127AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesPositive cofactor 4, PC4, SUB1 homolog, p14, SUB1, PC4, RPO2TC1
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200