Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.
SF3B6 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
>95%, Protein G purified
Recombinant Human Splicing factor 3B subunit 6 protein (1-125AA)
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Splicing factor 3B subunit 6, Pre-mRNA branch site protein p14, SF3b 14 kDa subunit, SF3B14a, Spliceosome-associated protein, 14-kDa, Splicing factor 3b, subunit 6, 14kDa, SF3B6, SAP14, SF3B14, SF3B14A, CGI-110, HSPC175, HT006
ELISA, IHC; Recommended dilution: IHC:1:20-1:200